منابع مشابه
Familiality of Quantitative Autism Traits
Background: Autistic traits exist along a continuum that extends into social functioning in the general population, and they aggregate in the family members of children with autism spectrum disorder (ASD). Quantitative measures are therefore essential when investigating the patterns of familiality of these traits. Prior studies have suggested differential inheritance patterns of autistic traits...
متن کاملInterrelationship and familiality of dyslexia related quantitative measures.
Dyslexia is a complex gene-environment disorder with poorly understood etiology that affects about 5% of school-age children. Dyslexia occurs in all languages and is associated with a high level of social and psychological morbidity for the individual and their family; approximately 40-50% have persistent disability into adulthood. The core symptoms are word reading and spelling deficits, but s...
متن کاملQuantitative Genetics and Quantitative Traits
Introduction In the chapter on Mendel and Morgan, we saw how the transmission of genes from one generation to another follows precise mathematical formula. The traits discussed in that chapter, however, were discrete traits—peas are either yellow or green, someone either has a disorder or does not have the disorder. But many behavioral traits are not like these clear-cut, have-it-or-don’t-have-...
متن کاملAutism traits in the RASopathies.
BACKGROUND Mutations in Ras/mitogen-activated protein kinase (Ras/MAPK) pathway genes lead to a class of disorders known as RASopathies, including neurofibromatosis type 1 (NF1), Noonan syndrome (NS), Costello syndrome (CS), and cardio-facio-cutaneous syndrome (CFC). Previous work has suggested potential genetic and phenotypic overlap between dysregulation of Ras/MAPK signalling and autism spec...
متن کاملA quantitative association study of SLC25A12 and restricted repetitive behavior traits in autism spectrum disorders
BACKGROUND SLC25A12 was previously identified by a linkage-directed association analysis in autism. In this study, we investigated the relationship between three SLC25A12 single nucleotide polymorphisms (SNPs) (rs2056202, rs908670 and rs2292813) and restricted repetitive behavior (RRB) traits in autism spectrum disorders (ASDs), based on a positive correlation between the G allele of rs2056202 ...
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ژورنال
عنوان ژورنال: Scandinavian Journal of Child and Adolescent Psychiatry and Psychology
سال: 2015
ISSN: 2245-8875
DOI: 10.21307/sjcapp-2015-013